Nagalase Testing – What is Nagalase and Why You Need to Know About It?
To Read About Blog Topic, Scroll Down
If you are a doctor or clinician looking to make a bigger impact on the world, have more job satisfaction and have up-to-date protocols and treatment solutions for your patients, check out our free functional medicine training led by functional medicine expert, Dr. Miles Nichols below.
Get Your Free Training Here
Plus additional BONUS training videos on treating tough cases of brain fog and cognitive impairment!!
Nagalase Testing – What is Nagalase and Why You Need to Know About It?
Nagalase is an enzyme found in the body and it has a role to play in breaking down the sugar we take in our food into other forms that can be utilized in the body in the struggle for survival. However, nagalase is a short form for the incredibly long scientific name it represents: N-acetyl-Galactosaminidase. Nagalase has specialized in splitting off a specific sugar molecule from other large molecules. This molecule is known as N-acetyl galactosamine. Nagalase splits this molecule from Vitamin D-binding protein (DBP) that can be found in serum and is also known as Gc-protein.
The important thing about nagalase is that the scientific community has discovered nagalase levels are increased in patients with tumors (cancer) 1, 2. Furthermore, nagalase depresses the activity of the immune system, and this activity helps cancer cells to grow and tumors to metastasize (spread) to other body organs and sites.
How does nagalase increase tumor cell formation and spread?
Nagalase causes immunosuppression by preventing the formation of a molecule that stimulates the immune system. This molecule is known as Gc-MAF and is derived from Gc-protein 3, 4. Gc protein has three sugar molecules, N-acetyl galactosamine, galactose and sialic acid. Galactose and sialic acid are removed from Gc-protein and the resultant molecule has been observed to have an effect on macrophages, which are immune cells that go around the body destroying invading microorganisms and consuming abnormal cells (for example cancer cells). It has been postulated that Gc-MAF is important in defending against tumor cell growth and spread5, 6. By preventing the formation of Gc-MAF, nagalase leaves the body without a vital defense structure in place, making it more vulnerable to cancer.
Is there a link between Nagalase and chronic viruses?
Increased nagalase activity has been linked with chronic viruses such as influenza viruses, and it has been established that nagalase activity resides on the outer envelope protein (Hemagglutinin) of the influenza virion. Nagalase levels are also increased in people living with HIV, as it is part of the gp120 protein of HIV.
To continue reading CLICK HERE
Nagalase is an enzyme found in the body and it has a role to play in breaking down the sugar we take in our food into other forms that can be utilized in the body in the struggle for survival. However, nagalase is a short form for the incredibly long scientific name it represents: N-acetyl-Galactosaminidase. Nagalase has specialized in splitting off a specific sugar molecule from other large molecules. This molecule is known as N-acetyl galactosamine. Nagalase splits this molecule from Vitamin D-binding protein (DBP) that can be found in serum and is also known as Gc-protein.
The important thing about nagalase is that the scientific community has discovered nagalase levels are increased in patients with tumors (cancer) 1, 2. Furthermore, nagalase depresses the activity of the immune system, and this activity helps cancer cells to grow and tumors to metastasize (spread) to other body organs and sites.
How does nagalase increase tumor cell formation and spread?
Nagalase causes immunosuppression by preventing the formation of a molecule that stimulates the immune system. This molecule is known as Gc-MAF and is derived from Gc-protein 3, 4. Gc protein has three sugar molecules, N-acetyl galactosamine, galactose and sialic acid. Galactose and sialic acid are removed from Gc-protein and the resultant molecule has been observed to have an effect on macrophages, which are immune cells that go around the body destroying invading microorganisms and consuming abnormal cells (for example cancer cells). It has been postulated that Gc-MAF is important in defending against tumor cell growth and spread5, 6. By preventing the formation of Gc-MAF, nagalase leaves the body without a vital defense structure in place, making it more vulnerable to cancer.
Is there a link between Nagalase and chronic viruses?
Increased nagalase activity has been linked with chronic viruses such as influenza viruses, and it has been established that nagalase activity resides on the outer envelope protein (Hemagglutinin) of the influenza virion. Nagalase levels are also increased in people living with HIV, as it is part of the gp120 protein of HIV.
To continue reading CLICK HERE
How to Find out More:
If you are a Clinician looking at continuing your functional medicine training please book a practice analysis call with us. If you are a interested in becoming a patient, please visit our clinic site at the link below
Love Our Blog And Interested In FREE TRAINING?
FREE Training Includes:
- Access to 27+ Modules of Functional Medicine Coursework
- Live Q and A’s to Answer Your Functional Medicine Questions
- Info on Lab Testing and Easy to Implement Protocols
- To Sign Up Go HERE
Access Our Functional Medicine Training for only $1 for your first month! Check it out and stay if you like. Leave if you don't!
Are You A Clinician Who...
- Wants to deeply impact your clients?
- Struggles with complex cases?
- Lacks ideas?
- Feels frustrated or stuck?
- Wants better results?
- Wants to learn with experts?
- To Sign Up Go HERE.
Are You a Suffering from Chronic Illness?
Does your current health situation look like this…
- Do you feel that you have tried many things and either nothing works, or the treatment does not hold?
- Have you been told that there is nothing that can be done to reverse your illness and you just need to manage symptoms?
- Does your illness impact your work, your family, your happiness and your social life?
We specialize in finding answers and solutions for complicated chronic illness when people feel like they have tried everything. If this sounds like you, book a free call with us to see if we are the right fit for your health goals.
Dr. Miles Nichols has spoken for the following organizations:
Recent Blog Posts
Report
Block Member?
Please confirm you want to block this member.
You will no longer be able to:
- See blocked member's posts
- Mention this member in posts
- Invite this member to groups
- Message this member
Please allow a few minutes for this process to complete.
Report
You have already reported this .