Is Lyme Disease Curable?

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is lyme disease curable

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Is Lyme Disease Curable?

In this blog, we will focus on Lyme Disease and Chronic Fatigue Syndrome. You will learn:

  • How chronic Lyme Disease and Chronic Fatigue Syndrome can look very similar to each other
  • How diagnosing, testing and treating these two conditions can be quite challenging
  • What to look for to tell the difference
  • How we can apply Functional Medicine principles, look for the root causes and successfully treat Lyme Disease & Chronic Fatigue Syndrome

Do your clients suffer from chronic fatigue that doesn’t seem to go away? Do they have Lyme Disease or Chronic Fatigue Syndrome and do you know how to spot the difference? Then this blog is for you. Please read on for the details! 

Do you get stuck clinically with symptoms of Lyme or Chronic Fatigue with your patients?  Would you like to have a larger impact on improving fatigue issues? The key to treating disease is an individual approach using nutrition, lifestyle and exercise. To improve your patient’s quality of life, you need to identify and address each patient’s root causes. Our functional medicine course will teach you how to do this. Look into our functional medicine school (mindbodyfunctionalmedicine.com) to have a greater impact on improving your client’s lives.

** Please note: If you want the short summary version of this article, then please click here **

Let’s first take a look at these individual conditions and then we will go into the interrelationship between Lyme Disease and Chronic Fatigue Syndrome.

What is Lyme Disease (LD)?

We have written extensively lately about Lyme Disease. LD is a tick-borne illness that causes multiple symptoms. Fatigue is one of the main symptoms. It can be difficult to diagnose and treat, depending on the individual case. Please see our blog here ‘What is Lyme Disease?’ to understand this condition better.

What is Chronic Fatigue Syndrome (CFS)?

Chronic Fatigue Syndrome (CFS) is a condition of extreme fatigue that lasts for at least six months (CDC, 2021). The fatigue worsens with physical or mental activity, but doesn’t improve with rest. Other symptoms can include problems with sleep, cognition, pain and dizziness.

People with CFS typically have a very poor quality of life. They can’t function ‘normally’. They probably cannot perform normal daily tasks, like taking a shower or cooking a meal. They may struggle to keep a job, go to school and participate in family and social life. CFS can last for years. At least one in four CFS patients is bed- or house-bound for long periods during their illness (CDC, 2021).

CFS Causes

CFS is thought to be caused by a number of factors, such as viral infections, intracellular bacteria, environmental factors, immune system dysregulation/dysfunction and hormonal imbalances (Bjørklund G, 2019). It is thought there is an autoimmune component, as well as a microbiome/ gut component (Bjørklund G, 2019).

Viral infection is a critical factor for some CFS patients (Rasa S, 2018). In some cases, an acute viral infection (Epstein Barr, Herpes, enteroviruses, Parvovirus B19 and other viruses) can trigger the onset of CFS (Sandler CX, 2020) and (Rasa S, 2018).

CFS Diagnosis

There isn’t a straightforward definition or clear-cut criteria to define CFS (Bjørklund G, 2019). At this time, there is no diagnostic test, biomarker, clear pathophysiology or treatment for CFS available in conventional medicine (Sandler CX, 2020).

In Functional Medicine, we look deeper to identify and find root causes. We would look for a previously undiagnosed underlying chronic infection, as this can often be a root cause of CFS. Other potential root causes include gut dysfunction or infections, autoimmune tendencies, HPA axis issues, thyroid or other hormonal imbalances, toxic overload (particularly metals) and nutrient deficiencies.

In this blog we will focus on answering the question ‘Is Lyme Disease Curable?’. You will learn:

  • What the basic approach to treating Lyme Disease is
  • What the complications and obstacles to successful treatment are
  • How we can apply Functional Medicine principles, look for the root causes and successfully treat & cure Lyme Disease

Do your clients suffer from fatigue, headaches or muscle or joint pain? Do they have Lyme Disease and do you know how to treat it? Then this blog on Lyme Disease is for you. Please read on for the details! 

Do you get stuck clinically with symptoms of Lyme with your patients? Would you like to have a larger impact on improving pain issues? The key to treating disease is an individual approach using nutrition, lifestyle and exercise. To improve your patient’s quality of life, you need to identify and address each patient’s root causes. Our functional medicine course will teach you how to do this. Look into our functional medicine school (mindbodyfunctionalmedicine.com) to have a greater impact on improving your client’s lives.

** Please note: If you want the short summary version of this article, then please click here **

What is Lyme Disease (LD)? 

Please refer to our article here for a detailed explanation of what Lyme Disease is. Between 2010 – 2018, there was an average of 476,000 LD diagnoses per year in the US (Maksimyan S, 2021). The incidence of Lyme Disease cases is rising.

Is Lyme Disease Curable?  

Lyme Disease is usually curable. It is best to catch it as early as possible. Seek medical advice as soon as you realize that you have been bitten by a tick, have a bull’s eye rash or suspect you may have been exposed to Lyme Disease after time in nature.

If we apply our Functional Medicine principles and always search for the root cause(s), we can untangle, treat and cure most complex cases of Lyme Disease. In complicated cases, a deep dive to identify root causes will help to develop a multi-pronged treatment plan to improve, and likely resolve, symptoms. We look for things like: other underlying infections, stress to the HPA axis, hormonal imbalances, nutrient deficiencies, toxin exposures or overload, poor detox or liver function, gut infections and gut health as well as any other issues that may prevent a person from getting well.

Lyme Disease can be difficult to treat. The CDC estimates that 10 – 20% of patients who are properly treated for Lyme may remain symptomatic after treatment for a variable and unspecified length of time (Hout, 2018). Lyme Disease is rarely life-threatening, but delayed treatment can result in more severe disease.

Is Lyme Disease Curable? The Treatment Options:

  • Lyme Disease is typically treated with antibiotics. Conventional medicine will usually prescribe a 2–4-week course of oral antibiotics.
  • It is also possible to treat Lyme more naturally with herbs and supplements.
  • In our clinic, we use both natural and antibiotic treatments on a case-by-case basis.
  • If correctly identified early on, most cases of Lyme Disease can be treated successfully with either herbal natural approaches or antibiotics.

Lyme Disease that goes misdiagnosed or untreated is more problematic. It can develop into a debilitating syndrome. In our clinic, we have expertise in treating a range of complicated, difficult-to-diagnose conditions like Lyme Disease. We look for the root causes in our patients to identify what could be causing the symptoms.

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Is Lyme Disease Curable? The Complications

  • If not treated correctly and early on, Lyme symptoms can persist. Different variations of late-stage Lyme Disease include (Radolf JD, 2021):
  • Late Neuroborreliosis
  • Post Treatment Lyme Disease Syndrome
  • Chronic Lyme Disease

Late Neuroborreliosis

In late neuroborreliosis, Lyme symptoms become neurological. Inflammation of the spinal nerve roots, pain, facial palsy, CNS infection affecting the spinal cord or the brain, encephalitis or stroke are all possible symptoms (Rauer S, 2018).

Conventional medicine typically uses antibiotics to treat patients with neurological signs of Lyme neuroborreliosis (Rauer S, 2018). The current recommendation is 2-3 weeks of antibiotics. There is not a lot of research on treatment. But the information does show that taking antibiotics for longer, by a further 100 days, showed no clinical advantage over a placebo (Rauer S, 2018). Which antibiotic or how it is given (oral vs IV) does not seem to matter either (Rauer S, 2018). An antibiotic should be chosen according to patient-specific aspects such as allergies, age, pregnancy and how it is administered (Rauer S, 2018).

In most trial studies, a 1–2-week course of antibiotics improved neurological symptoms in most patients within a few weeks to months (Rauer S, 2018). Lyme neuroborreliosis patients typically stabilized within one year after treatment.

But 60–80% of those with late neuroborreliosis can still experience lingering neurological symptoms (Rauer S, 2018).

That is a high proportion of patients who do not completely recover with conventional treatments. This is where Functional Medicine can help with a more targeted diagnosis and treatment plan.

Post Treatment Lyme Disease Syndrome(PTLDS)

In post-treatment Lyme Disease syndrome or PTLDS, patients have symptoms that persist after treatment. Symptoms include fatigue, pain and cognitive difficulties. These persist past the initial antibiotic treatment of acute LD, and last over six months or longer post-treatment (Maksimyan S, 2021).

PTLDS occurs in approximately 10% of patients with Lyme Disease, following antibiotic treatment (Fitzgerald BL, 2021). Relatively little is known about it. Researchers have not been able to identify why some people get PTLDS or what the predisposing factors are. It is also quite tough to diagnose, treat and prevent (Maksimyan S, 2021).

Long-term trials of antibiotics are the most researched treatment plans for PTLDS. However, the specific antibiotics used, the length of treatment, the symptoms being treated and the outcomes vary amongst these studies. This makes it difficult to make comparisons and conclusions about treatment (Maksimyan S, 2021). But these studies do indicate that longer-term antibiotics for these persistent symptoms of LD have no additional benefits over a 2-week course of antibiotics (Maksimyan S, 2021).

Chronic infection with Borrelia burgdorferi should not be assumed in patients with PTLDS symptoms. They should not necessarily be treated with more antibiotics, as research shows that more antibiotics do not help. Instead, it is better to do a thorough medical evaluation and treat the specific symptoms (Rauer S, 2018).

One study from the late 1990s looked at whether post-LD symptoms, especially severe fatigue and slower mental speed, would improve with long-term antibiotics (Maksimyan S, 2021). The study found that antibiotics only improved some symptoms and may not be the right approach for every patient (Maksimyan S, 2021).

There may be adverse effects from longer antibiotic use (Maksimyan S, 2021). In one study, 73% of patients on antibiotics reported an adverse event. The most common events were rash, diarrhea and allergic reactions. 6.8% of patients had to drop out of the study due to side effects (Maksimyan S, 2021). In more serious cases, there are worse side effects from prolonged antibiotic use including possible death (Maksimyan S, 2021).

Once again, it is critical to get a correct diagnosis to avoid over-prescribing antibiotics (Maksimyan S, 2021).

How common is PTLDS?

It is difficult to predict the likelihood of developing PTLDS but one study does give us an estimate (Maksimyan S, 2021). This relatively small study showed 35% of participants had PTLDS, and that these patients had significantly lower function and quality of life within six months of treatment. This study specifically recruited patients with early-diagnosed LD who received immediate treatment.

Various medications have been trialed to treat PTLDS but so far none have been found to be effective (Maksimyan S, 2021).

One encouraging study looked at a non-pharmaceutical therapy for chronic Lyme disease: resistance training in patients. People with a previous LD diagnosis and symptoms persisting for at least three months after treatment were recruited. After a supervised 4-week resistance exercise training, they had significant improvement in their joint pain symptoms, exercise performance and the number of days they felt healthy and full of energy (Maksimyan S, 2021).

Chronic Lyme Disease (CLD)

Chronic Lyme Disease can significantly affect a person’s quality-of-life. CLD is when patients have unexplained on-going symptoms. CLD can include a range of symptoms such as fatigue and chronic pain which occur due to a lengthy Borrelia infection.

Often, people don’t notice a tick bite or may not get a bulls-eye rash. They may not think of getting checked for Lyme and may have a long delay in getting a correct diagnosis. This can lead to chronic Lyme. Or their antibiotics treatment may not work, as it is not a fail-proof cure. Patients with chronic, long-standing Lyme Disease are often sick for long periods of time following treatment or may experience a worsening of their Lyme symptoms despite treatment (Shor S, 2019).

What are the Mechanisms of CLD?

Possible causes of Chronic LD include (Shor S, 2019) and (Hout, 2018):

  • Tissue injury from the pathogenic bacteria, Borrelia burgdorferi. It can invade a wide range of cells such as fibroblasts, glial and neuronal cells, endothelial cells, lymphocytes, synovium, skin, ligaments, cardiac tissue, lymph nodes and tonsillar lymphoid tissue (Shor S, 2019).
  • Lyme-induced secondary conditions
  • Unrecognized or undertreated co-infections
  • Immune dysfunction: post-treatment immune dysfunction could be due to a failure to clear antigenic debris, the formation of autoantibodies or a persistent elevation of immune mediators.
  • A persistent Borrelia infection may evade the immune system by forming and hiding behind biofilms.
  • Unregulated inflammation

As we know, most likely more than one mechanism will be involved for a given patient and each person needs to be looked at as an individual and unique case.

CLD Treatment

Studies show that additional or longer courses of antibiotics do not help patients after being treated the first time for Lyme (Halperin, 2015). Antibiotics are ineffective in patients with persistent fatigue and cognitive symptoms following appropriately diagnosed and treated Lyme disease (Halperin, 2015). This can even put patients at risk of side effects from the antibiotics (Halperin, 2015).

We would recommend that patients who have tried antibiotics and are still not cured look to Functional Medicine to find the underlying causes for symptoms and treat them with a more targeted approach than just antibiotics.

Co-Infections of Lyme Disease

We will look at Lyme Disease co-infections in another blog. It is an important topic and can affect the outcome and success of treatment. However, it is beyond the scope of this article so please stay tuned for a future blog on Lyme co-infections

Degenerative Neurological Diseases

Lastly, a great concern is when LD goes misdiagnosed or untreated. In these cases, LD can, years later, be diagnosed as chronic inflammatory age-related degeneration (for example arthritis, dementia or stroke). This is partially due to the increased complications of aging for those with persistent and untreated Lyme Disease.  

Some neurological diseases can even be partially caused by Lyme Disease. We have written extensively about this and you can find the links to blogs here, including Lyme and Alzheimer’s, Lyme and Parkinson’s, Lyme and ALS and Lyme and MS.

Lyme Disease is usually curable. It is best to catch it as early as possible. It is critical to seek medical advice as soon as you realize that you have been bitten by a tick, have a bull’s eye rash or suspect you may have been exposed to Lyme Disease after time in nature.

As always, please get in touch with us. If you or someone you know is struggling with pain, fatigue or other issues related to Lyme Disease, contact our clinic today. We can work on any issue(s) and improve your health. Book a free health evaluation call with us today, to see how we can help you with your concerns. We can answer your questions and help you book an initial consult with one of the functional medicine doctors in our clinic.

** Please stay tuned for our next Blog!  **

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  • Do you feel that you have tried many things and either nothing works, or the treatment does not hold?
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We specialize in finding answers and solutions for complicated chronic illness when people feel like they have tried everything. If this sounds like you, book a free call with us to see if we are the right fit for your health goals. 

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