Peptide Therapy: KPV: The Anti-Inflammation & Pro-Healing Peptide

To Read About Blog Topic, Scroll Down

If you are a doctor or clinician looking to make a bigger impact on the world, have more job satisfaction and have up-to-date protocols and treatment solutions for your patients, check out our free functional medicine training led by functional medicine expert, Dr. Miles Nichols below.

kpv

Get Your Free Training Here

Plus additional BONUS training videos on treating tough cases of brain fog and cognitive impairment!!

Peptide Therapy: KPV: The Anti-Inflammation & Pro-Healing Peptide

We have recently written many blogs about peptides. To recap, a peptide is a small protein, made up of a chain of amino acids. They can be used therapeutically to help with different health conditions. Click on the links to see our articles on peptide therapy, HGH, CJC 1295/Ipamorelin, BPC 157, PT 141, Ta1, VIP and Thymosin Beta 4.

What Is KPV?

KPV is a peptide that is naturally produced in the body. It is found in the hormone alpha-MSH. It is used for inflammation, gut health and conditions such as Inflammatory Bowel Disease (IBD) and colon cancer.

What are the Benefits & Applications of KPV?

  • Anti-inflammatory
  • Anti-microbial
  • Used in healing wounds & injuries
  • Helps with Inflammatory Bowel Diseases (IBD) and colitis
  • Some benefits with cancer

Anti-Inflammatory

KPV exerts its anti-inflammatory function inside cells, where it inactivates inflammatory pathways (Xiao B, 2017). KPV enters the cell and interacts directly with inflammatory signalling molecules inside the cell (Land, 2012). It enters the nucleus of the cell and, once there, can inhibit the interaction of inflammatory substances and molecules (Land, 2012).

Anti-Microbial

In addition to its anti‐inflammatory effect, KPV also has antimicrobial effects against pathogens (Luger TA, 2007). Its antimicrobial effects were demonstrated on two major pathogens called S. aureus and C. albicans (Böhm M, 2019). In one study, KPV significantly inhibited S. aureus from forming colonies (Böhm M, 2019). 

Wound Healing

Research in wound healing shows KPV can speed wound healing, reduce infection, fight inflammation, and lead to better cosmetic results (Böhm M, 2019). Often with wounds, various microbes enter the wound. KPV, with its anti-inflammatory and anti-microbial properties, can be very helpful for combatting these microbes and healing wounds (Böhm M, 2019).

Gut Issues: Ulcerative Colitis & Inflammatory Bowel Diseases (IBDs)

KPV significantly decreased inflammation in colitis (Dalmasso G, 2008). It decreases the inflammatory response by inhibiting proinflammatory cytokine (molecule) synthesis and secretion (Dalmasso G, 2008). KPV can stop the proinflammatory mechanisms in both intestinal epithelial cells and immune cells (Dalmasso G, 2008). It can interact directly with immune cells which can reduce inflammation (Dalmasso G, 2008). KPV may help in the case of IBDs through inhibited immune responses (Dalmasso G, 2008).

Taken orally, KPV reduces the incidence of colitis, as shown by a decrease in proinflammatory cytokines (Dalmasso G, 2008). In the case of colitis, KPV reduced weight loss, colonic activity and decreased inflammation and proinflammatory cytokine levels (Dalmasso G, 2008).

Cancer

KPV treatment is able to decrease tumorigenesis (Viennois E, 2016). KPV was sufficient to decrease the inflammation of carcinogenesis (Viennois E, 2016). Using KPV before the development of colon cancer might be a preventive way to stop colonic carcinogenesis before it begins (Viennois E, 2016). The precise mechanism by which KPV decreases tumorigenesis is not yet fully understood (Viennois E, 2016).

Method of Delivery for KPV

Iontophoresis is method of taking medications. KPV is often taken via this method. It uses low-level current to drive charged compounds across the skin barrier (Ita, 2016). Iontophoresis is very useful because it increases the absorption of drugs and is a way of driving KPV, or another drug, deeper into the skin, bypassing the first metabolism in the gut (Rawat S, 2008).

Side Effects

KPV is a naturally derived peptide without any notable side effects (Xiao B, 2017). KPV has been shown in animal studies to be safe and effective when administered orally, intravenously, subcutaneously and transdermally (Xiao B, 2017).

There is always the chance of potential interactions with other medications a person may be taking. It is very important to work with an experienced Functional Medicine practitioner when taking KPV or any other peptides. Our clinic has extensive experience with peptides and can help you with KPV or other peptides.

**Please stay tuned for our next blog on more Peptide Therapy!**

Love Our Blog And Interested In FREE TRAINING?

FREE Training Includes:

  • Access to 27+ Modules of Functional Medicine Coursework
  • Live Q and A’s to Answer Your Functional Medicine Questions
  • Info on Lab Testing and Easy to Implement Protocols
  • To Sign Up Go HERE

Access Our Functional Medicine Training for only $1 for your first month! Check it out and stay if you like. Leave if you don't!

Are You A Clinician Who...

  • Wants to deeply impact your clients?
  • Struggles with complex cases?
  • Lacks ideas?
  • Feels frustrated or stuck?
  • Wants better results?
  • Wants to learn with experts?
  • To Sign Up Go HERE.

Are You a Suffering from Chronic Illness?

Does your current health situation look like this…

  • Do you feel that you have tried many things and either nothing works, or the treatment does not hold?
  • Have you been told that there is nothing that can be done to reverse your illness and you just need to manage symptoms?
  • Does your illness impact your work, your family, your happiness and your social life?

We specialize in finding answers and solutions for complicated chronic illness when people feel like they have tried everything. If this sounds like you, book a free call with us to see if we are the right fit for your health goals. 

Dr. Miles Nichols has spoken for the following organizations:

Recent Blog Posts